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Betty R. Yu
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Betty R. Yu, M.S.

Patent Agenet


*Practice limited to proceedings before the U.S. Patent and Trademark Office

Professional Profile

Bar Admission

  • U.S. Patent and Trademark Office, 2012


  • M.S. (1987)
    University of Maryland (Nutritional Biochemistry)
  • B.S. (1984)
    University of Maryland (Biochemistry)


  • English
  • Chinese (Mandarin and Shanghainese Dialects)


  • Yu, Betty R., Co-Author, “Enamino-oxindole HIV Protease Inhibitors” 22 Bioorg. Med. Chem. Lett. 5078-5083 (2012)
  • Yu, Betty R., Co-Author, “Novel uncomplexed and complexed structures of plasmepsin II, an aspartic protease from Plasmodium falciparum,” 327 J. Mol. Biol. 173-181 (2003)
  • Yu, Betty R., Co-Author, “Drug resistance mutations can affect dimer stability of HIV-1 protease at neutral pH,” 8 Protein Science 1702-1707 (1999).
  • Yu, Betty R., Co-Author, “Kinetic characterization of RS-344, an HIV-1 protease inhibitor designed with a 'resistant repellent' core,” 4 Antiviral Therapy (1999).
  • Yu, Betty R., Co-Author, “A new series of potent, orally bioavailable, non-peptidic cyclic sulfones as HIV-1 protease inhibitors,” 39(18) J. Am. Chem. Soc. 3431-3434 (1996)
  • Yu, Betty R., Co-Author, “Kinetic characterization and cross-resistance patterns of HIV-1 protease mutants selected under drug pressure,” 34 Biochemistry 9282-9287 (1995)
  • Yu, Betty R., Co-Author, “Expression of growth-related genes during tumor progression in v-raf transformed rat liver epithelial cells,” 50 Cancer Research 7460-7467 (1990)
  • Yu, Betty R., Co-Author, “Purification and characterization of UDP -GlcNAc:dolichol phosphate GlcNAc-1-phosphotransferase from bovine mammary gland,” 263 J. Biol. Chem. 15964-15972 (1988)

Professional Experience

  • Scientific research experience: Sequoia Pharmaceutical, Inc., Tibotec Inc., and National Cancer Institute.
  • Patent technology transfer experience: Office of Technology Transfer and Development, National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK), National Institutes of Health (NIH).

Professional Membership

  • American Intellectual Property Law Association
  • Licensing Executives Society
  • Chinese Biopharmaceutical Association


  • Yu, Betty R., Co-Author, “HIV PIs with Excellent resistance Profile,” 2008 Gordon research Conference on Medicinal Chemistry, New London, NH, August 2008.
  • Yu, Betty R., Co-Author, “Antiviral Activity of SPI-256 against WT and MDR Strains,” 15th International HIV Drug Resistance Workshop, Sitges, Spain, June 2006.
  • Yu, Betty R., Co-Author, “Highly potent HIV protease inhibitors with broad activity against MDR stains,” XIII International HIV Drug Resistance Workshop, Canary islands, Spain, June 2004.
  • Yu, Betty R., First Author, “Development of a relational database for structure-based drug design,” RAMC 99 Conference, San Diego, CA, August 1999.
  • Yu, Betty R., Co-Author, “Structures of plasmepsin II in complex with non-peptidic inhibitors,” VIII International Aspartic Proteinase Conference, September 1999.
  • Yu, Betty R., Co-Author, “The not-so-great escape: Drug resistance studies with HIV protease,” 217th American Chemical Society National Meeting, Anaheim, CA, March 1999.
  • Yu, Betty R., Co-Author, “Design and parallel synthesis of human cathepsin D inhibitor libraries,” 39th Annual Buffalo Medicinal Chemistry Symposium, May 1998.
  • Yu, Betty, R., Co-Author, “Structural studies of drug resistance for HIV-1 protease mutants,” American Crystallographic Association, Montreal, Canada, July 1995.
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